Harvard University, fas   
Fall 2003   

 

Biophysics 101

Genomics and Computational Biology

George Church, Ph.D. (HMS)


 

 

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Lecture Notes for 2002

Sep 17

Intro 1: Computing, Statistics, Perl, Mathematica
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Sep 24

Intro 2: Biology, comparative genomics, models & evidence, applications

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Section notes

Oct 1

DNA 1: Polymorphisms, populations, statistics, pharmacogenomics, databases

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Section notes

Oct 8

DNA 2: Dynamic programming, Blast, multi-alignment, HiddenMarkovModels

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Section notes

Oct 15

RNA 1: 3D-structure, microarrays, library sequencing & quantitation concepts

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Oct 22

RNA 2: Clustering by gene or condition, DNA/RNA motifs.

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Section notes

Oct 29

Protein 1: 3D structural genomics, homology, dynamics, function & drug design

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Nov 5

Protein 2: Mass spectrometry, modifications, quantitation of interactions

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Nov 12

Network 1: Metabolic kinetic & flux balance optimization methods

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Nov 19

Network 2: Molecular computing, self-assembly, genetic algorithms, neural-nets

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Nov 26

Network 3: Cellular, developmental, social, ecological & commercial models

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